A case of multiple sclerosis with characteristic verbal paraphasia

Abstract

In multiple sclerosis (MS), aphasia is rarely observed, although cognitive dysfunction is frequent. Recently, we experienced a right-handed 42-year-old woman with secondary progressive MS who showed difficulty in word finding and characteristic paraphasia. Although she had a long duration of illness, since she developed MS at the age of 14, she showed no obvious physical dysfunctions. In contrast, in addition to the semantic paraphasia, unrelated paraphasia was observed. Examinations suggested that dysfunction in the categorization of words that probably associate with frontal lobe dysfunction might have caused her characteristic paraphasia.