Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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A Novel Antivirally Active Fucan Sulfate Derived from an Edible Brown Alga, Sargassum horneri
Srisomporn PREEPRAMEKyoko HAYASHIJung-Bum LEEUshio SANKAWAToshimitsu HAYASHI
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2001 Volume 49 Issue 4 Pages 484-485

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Abstract

A novel fucan sulfate (Hor-1) was isolated from the hot water extract of an edible brown alga, Sargassum horneri (Turner) C. AGARDH. The fucan sulfate was revealed to have sugar linkage types, sulfate content and uronic acid content different from those of sodium hornan (Na-HOR), another fucan sulfate isolated from this alga. However, it exhibited inhibitory activity against replication of herpes simplex virus type 1 with similar potency to Na-HOR.

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© 2001 The Pharmaceutical Society of Japan
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