Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Prenylated Xanthones from Garcinia xanthochymus
Wisinee ChanmahasathienYushan LiMasayuki SatakeYasukatsu OshimaMasami IshibashiNijsiri RuangrungsiYasushi Ohizumi
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2003 年 51 巻 11 号 p. 1332-1334

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A new prenylated xanthone, 1,3,5,6-tetrahydroxy-4,7,8-tri(3-methyl-2-butenyl)xanthone (1), was isolated from the wood of Garcinia xanthochymus together with a known xanthone, garciniaxanthone E (2). Their structures were determined by spectroscopic analysis. Compounds 1 (3 μM) and 2 (10 μM) elicited marked enhancement of nerve growth factor-mediated neurite outgrowth in PC12D cells.

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© 2003 The Pharmaceutical Society of Japan
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