Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Studies on Nepalese Crude Drugs. XXVIII. Chemical Constituents of Bhote Khair, the Underground Parts of Eskemukerjea megacarpum HARA
Yukinori MiyaichiNorihisa NunomuraYukio KawataHaruhisa KizuTsuyoshi TomimoriTakashi WatanabeAkihito TakanoKuber Jung Malla
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2006 Volume 54 Issue 1 Pages 136-138

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Abstract

From the underground parts of Eskemukerjea megacarpum HARA, two new stilbenes (14, 15) were isolated, together with a known coumarin, 5,7-dihydroxycoumarin (1), a tyramine derivative, trans-feruloyltyramine (2), two pyrogallol derivatives, gallic acid (3) and β-glucogallin (4), four flavonoids, trifolin (5), hyperin (6), myricetin 3-O-β-D-galactopyranoside (7), and myricitrin (8), five stilbenes, resveratorol (9), astringenin (10), piceid (11) astringin (12), and resveratorol 3-O-β-D-(6-O-galloyl)glucopyranoside (13), a flavan-3-ol, (−)-epigallocatechin 3-O-gallate (16), two proanthocyanidins, catechin-(4α→8)-epigallocatechin 3-O-gallate (17) and epicatechin 3-O-gallate-(4β→8)-epigallocatechin 3-O-gallate (18), and an anthocyanin, idaein (19). Compounds 14 and 15 were identified as (E)-3,5,3′,4′-tetrahydroxystilbene 3-O-β-D-(6-O-galloyl)glucopyranoside and (E)-3,5,4′-trihydroxystilbene 3-O-β-D-(6-O-galloyl)glucopyranoside, respectively, based on spectral and chemical data.

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© 2006 The Pharmaceutical Society of Japan
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