A New Triterpene and Dibenzocyclooctadiene Lignans from Schisandra propinqua (W<small>ALL</small>.) B<small>AILL</small>

LiJia Xu; Feng Huang; SiBao Chen; ShiLin Chen; PeiGen Xiao

doi:10.1248/cpb.54.542

Notes

A New Triterpene and Dibenzocyclooctadiene Lignans from Schisandra propinqua (WALL.) BAILL

LiJia Xu, Feng Huang, SiBao Chen, ShiLin Chen, PeiGen Xiao

Author information

LiJia Xu
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical Sciences
State Key Laboratory of Chinese Medicine and Molecular Pharmacology
Feng Huang
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical Sciences
State Key Laboratory of Chinese Medicine and Molecular Pharmacology
SiBao Chen
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical Sciences
State Key Laboratory of Chinese Medicine and Molecular Pharmacology
Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University
ShiLin Chen
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical Sciences
State Key Laboratory of Chinese Medicine and Molecular Pharmacology
Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University
PeiGen Xiao
Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical Sciences
State Key Laboratory of Chinese Medicine and Molecular Pharmacology
Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University

Keywords: Schisandra propinqua, Schisandraceae, triperpene, dibenzocyclooctadiene lignan, cytotoxicity

JOURNAL FREE ACCESS

2006 Volume 54 Issue 4 Pages 542-545

DOI https://doi.org/10.1248/cpb.54.542

Details

Abstract

A new triterpene and two new natural dibenzocyclooctadiene lignans were isolated from the stems of Schisandra propinqua. In addition, three known lignans, octadecanoic acid, 2,3-dihydroxypropyl ester and β-sitosterol were isolated. The structures of the new triterpene and new natural products were elucidated base on spectral analysis, including 1D and 2D NMR experiments. The isolates were tested for their cytotoxic effects against several tumor cell lines by MTT assay.

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