Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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Medicinal Flowers. XIV.1) New Acylated Oleanane-Type Triterpene Oligoglycosides with Antiallergic Activity from Flower Buds of Chinese Tea Plant (Camellia sinensis)
Masayuki YoshikawaSeikou NakamuraYasuyo KatoKoudai MatsuhiraHisashi Matsuda
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2007 Volume 55 Issue 4 Pages 598-605

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Abstract

The methanolic extract from the flower buds of Chinese tea plant (Camellia sinensis (L.) O. KUNTZE) was found to inhibit release of β-hexosaminidase from RBL-2H3 cells. From the methanolic extract, six new acylated oleanane-type triterpene oligoglycosides, floratheasaponins D—I, were isolated together with 21 known compounds including floratheasaponins A—C. The chemical structures of floratheasaponins D—I were elucidated on the basis of chemical and physicochemical evidence. The principal constituents, floratheasaponins A—F, were found to show the inhibitory activity on the release of β-hexosaminidase from RBL-2H3 cells.

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© 2007 The Pharmaceutical Society of Japan
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