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Chemical and Pharmaceutical Bulletin
Vol. 56 (2008) No. 2 P 213-216




Activity-directed isolation of the methylene chloride fraction of the roots of Rubia cordifolia L. resulted in the identification of a new epoxymollugin (3) and eight known compounds (1, 2, 4—9). The structures of the compounds were elucidated from chemical and spectroscopic evidence. In addition, their topoisomerase I and II inhibitory activities and cytotoxicities were measured.

Copyright © 2008 The Pharmaceutical Society of Japan

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