Diels–Alder Reaction of 2(1H)-Pyridones Acting as Dienes

Abstract

Diels–Alder reactions between N-phenylmaleimide, acting as the dienophile, and 2(1H)-pyridones having a methoxy or a chloro substituent, were carried out, under atmospheric and high pressure conditions, to give the corresponding isoquinuclidine derivatives. Stereoselectivity of the Diels–Alder reactions was studied using molecular orbital calculations.