Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Annonamine, a New Aporphine Alkaloid from the Leaves of Annona muricata
Ayano MatsushigeYaichiro KotakeKatsuyoshi MatsunamiHideaki OtsukaShigeru OhtaYoshio Takeda
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2012 年 60 巻 2 号 p. 257-259

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Atypical Parkinsonism in the Caribbean Island Guadeloupe is thought to be associated with the consumption of plants of the Annonaceae family, especially Annona muricata (soursop). In this study, a new aporphine alkaloid named annonamine (1) was isolated from the leaves of A. muricata L. together with four known benzylisoquinoline alkaloids (25). The structures of the isolated compounds were elucidated by the spectroscopic method.

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© 2012 The Pharmaceutical Society of Japan
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