Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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Quantitative Analysis of Marker Compounds in Angelica gigas, Angelica sinensis, and Angelica acutiloba by HPLC/DAD
Su Yang JeongHye Mi KimKyu Ha LeeKyu Yeob KimDae Sun HuangJong Hwan KimRack Seon Seong
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2015 Volume 63 Issue 7 Pages 504-511


Although Danggui is the root of Angelica gigas NAKAI in the Korean Pharmacopoeia, it is determined that Danggui is also the root of Angelica sinensis (OLIV.) DIELS in China and Hong Kong, as well as the root of Angelica acutiloba KITAGAWA in Japan. Accordingly, we tried to develop an identification method using the main compounds in A. gigas, A. sinensis, and A. acutiloba through HPLC/diode-array detector (DAD). This method was fully validated for linearity, accuracy, precision, recovery, and robustness. Multivariate analysis was also implemented after pattern analysis and monitoring. As a result, each compound pattern of A. gigas, A. sinensis, and A. acutiloba was identified, making it possible to distinguish them from each other.

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© 2015 The Pharmaceutical Society of Japan
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