Pharmaceutical Bulletin
Online ISSN : 1881-1345
Print ISSN : 0369-9471
ISSN-L : 0369-9471
Metabolism of Drugs. XIV. Metabolic Fate of p-Aminosalicylic Acid in the Rabbit. (2)
Hisao TsukamotoAkira YamamotoOsamu Kamata
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1957 Volume 5 Issue 6 Pages 565-569

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Abstract

The ester-type PAS-glucuronide was isolated from the urine of rabbit receiving PAS and the structure was established as methyl (4-acetamido-2-acetoxybenzoyl 2, 3, 4-tri-O-acetyl-β-D-glucopyranosid) uronate, which was synthesized. m-Aminophenyl glucuronide was isolated from the urine of rabbit. p-Aminosalicyluric acid, m-aminophenyl sulfate, and the ether-type PAS-glucuronide were detected in the urine by means of paper chromatography.

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© The Pharmaceutical Society of Japan
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