Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Synthesis of New Antimicrobials. I. Synthesis of 2, 5-Dichloroaniline Derivatives and their Some Antibacterial Activities
木村 隆一藪内 隆弘久木 正勝杉本 英幾大山 昭夫持田 晃一
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1962 年 10 巻 12 号 p. 1226-1232

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Twentyfour of new N-derivatives of 2, 5-dichloroaniline, 2, 5-dichloro-4-bromo-aniline and 2, 5-dichloro-4-thiocyanatoaniline were synthesized in order to investigate the potential antimicrobial activity. Among them, 2-hydroxy-5-bromobenzoyl derivatives were found to give strong antibacterial activities on Staph. aureus in vitro.

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© The Pharmaceutical Society of Japan
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