Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Phenol Oxidation of Isoquinoline Alkaloids. II. Oxidative Coupling of dl-N-Methylisosalsoline
富田 真雄正木 幸雄冨士谷 憲徳
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1968 年 16 巻 2 号 p. 257-261

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Oxidative coupling of dl-N-methylisosalsoline (III) with potassium ferricyanide was carried out, and the structures of the products were determined. It was found that III gives rise both to biphenyl derivatives (VI, VII) and diphenyl ether derivative (IV), and a steric participation of 1-substituent of 2-methyl-6-methoxy-7-hydroxy-1, 2, 3, 4-tetrahydroisoquinoline derivative in the product development in the phenol oxidation reactions was observed.
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© The Pharmaceutical Society of Japan
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