Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Nucleosides and Nucleotides. VIII. Nucleophilic Substitution of Secondary Sulfonyloxy Groups of Pyrimidine Nucleosides. (1)
内藤 武男平田 三四司中井 義昭小林 利彦金尾 宗史
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1968 年 16 巻 2 号 p. 285-290

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Treatment of 2'-O-tosyl-5'-O-trityluridine (I), 2'-O-tosyluridine (II), or 2', 3'-di-O-tosyluridine (XI) with various alkali chlorides or bromides afforded only 2'-halogenonucleosides, whereas in the reaction of alkali iodides with I or II were isolated 2, 2'-anhydronucleosides accompanied with 2'-deoxy-2'-iodouridine derivatives. And in the reaction of XI with sodium iodide in DMF only 2, 2'-anhydro-1-(3'-O-tosyl-β-D-arabinofuranosyl)-uracil (XIII) was obtained.
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