Studies on Benzoheterocyclic Derivatives. XII. Synthesis and Pharmacological Actions of Indoline Derivatives. (3)

Abstract

A total of 39 derivatives of 3-alkyl-1-[ω-(N-substituted amino)alkyl]-3-phenylindolin-2-ones and their related compounds were synthesized for pharmacological testing. Compounds were tested for analgetic-antiphlogistic activity by anti-writhing tests in mice. Acute toxicity and effects upon the general behaviour in mice were also determined.