Studies on Peptides. XLII. Synthesis of the Protected Nonapeptide Corresponding to Positions 29 to 37 of the Basic Trypsin Inhibitor from Bovine Pancreas (Kunitz and Northrop)

Abstract

The protected nonapeptide, Z (OMe)-Leu-Cys (Bzl)-Gln-Thr-Phe-Val-Tyr-Gly-Gly-OH, corresponding to positions 29 to 37 of the basic trypsin inhibitor (Kunitz and Northrop), was synthesized by the azide coupling of Z (OMe)-Leu-Cys (Bzl)-Gln-Thr-NHNH₂ and H-Phe-Val-Tyr-Gly-Gly-OH.