Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reaction of ο-Aminobenzamide Derivatives with Ethoxymethylenemalononitrile and Its Analogue
長原 勝彦高木 要上田 武雄
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1976 年 24 巻 6 号 p. 1310-1313

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A new synthetic method of o-aminobenzamide derivatives with ethyl ethoxymethylenecyanoacetate or ethoxymethylenemalononitrile gave high yield of 3, 4-dihydro-4-oxoquinazoline and 3-aryl-3, 4-dihydro-4-oxoquinazoline derivatives, and the mechanism of this synthetic reaction was discussed.
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© The Pharmaceutical Society of Japan
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