Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis of Pyrazolone Derivatives. XXIX. Synthesis of 1, 3-Dioxolane-indazole Derivatives
ISOO ITONORIICHI ODAHIROSHI KAKISHIMATETSUO KATOKYOICHI ASANOTSUTOMU SUGAWARA
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Keywords: analgesic
JOURNAL FREE ACCESS

1977 Volume 25 Issue 5 Pages 1124-1128

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Abstract
Several 2'-phenyl-spiro [1, 3-dioxolane-2, 5'-indazoles] having alkyl or alkoxy side chains at 1'(III), 3'a (IV) and 3'(V) were prepared as analgesic agents. III and IV were derived to oxo-indazoles (VII, VIII), which were hydrogenated to give the corresponding hydroxy indazoles (IX, X). Some of these compounds showed slight analgesic activity.
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© The Pharmaceutical Society of Japan
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