Biogenetic-type Synthesis of (±)-Phyllodulcin, a Sweet Principle of Hydrangea serrata SERINGE var. thunbergii SUGIMOTO (Studies on the β-Carbonyl Compounds connected with the β-Polyketides. VI)

Abstract

A biogenetic-type synthesis of (±)-phyllodulcin (2), a sweet principle of Hydrangea serrata SERINGE var. thunbergii SUGIMOTO, from 3-(3-benzyloxy-4-methoxyphenyl)-2-propenal (7) modelled on the polyketide mode of biosynthesis is described.