Synthesis of N, N, 3, 9-Tetraalkyladeninium Halides by Alkylations of N, N, 3- and N, N, 9-Trialkyladenines

Abstract

The reactions of N, N, 9-trialkyladenines (II) with alkyl halides in N, N-dimethylacetamide gave N, N, 3, 9-tetraalkyladeninium halides (IV) in good yields. N, N, 3-Trialkyl-adenines (III) underwent the alkylation more smoothly to provide an alternative synthesis of IV.