Studies on the Synthesis of Heterocyclic and Natural Compounds. CMXLV. A Stereoselective Synthesis of Non-Tryptamine Components of Reserpine and Yohimbine from Furfural

Abstract

A general method for the stereoselective synthesis of the non-tryptamine components of reserpine and yohimbine via the same compound (6) is described. This common intermediate was readily obtained by Diels-Alder reaction of the furfural derivative (10) with maleic anhydride.