Reactions of 2, 2, 2-Trichloroethylamines with Grignard Reagents and Alkyllithiums

Abstract

2, 2, 2-Trichloro- and 2, 2-dichloroethylamines were found to suffer monoalkylation with Grignard reagents and alkyllithiums giving, in the main, chain-lengthened β, γ- or α, β-unsaturated amines. Which product is formed depends upon the individual structures of the substrates and organometallic compounds.