Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Obovatol and Obovatal, Novel Biphenyl Ether Lignans from the Leaves of Magnolia obovata THUNB.
KAZUO ITOTOSHIYUKI IIDAKAZUHIKO ICHINOMASA TSUNEZUKAMASAO HATTORITSUNEO NAMBA
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1982 Volume 30 Issue 9 Pages 3347-3353

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Abstract

Two new biphenyl ether lignans, named obovatol (1) and obovatal (2) were isolated from the leaves of Magnolia obovata THUNB. (Magnoliaceae) and their chemical structures were determined to be 4', 5-diallyl-2, 3-dihydroxybiphenyl ether and 3, 4-dihydroxy-5-(pallylphenoxy) cinnamic aldehyde by means of chemical and spectral studies. The former substance showed antibacterial activity against a cariogenic bacterium, Streptococcus mutans, but was less active than magnolol (5) and honokiol (6).

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© The Pharmaceutical Society of Japan
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