Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Pyrrolo [1', 2' : 1, 2] pyrazino [6, 5-b] carbazoles
JEAN-CHARLES LANCELOTJEAN-MARIE GAZENGELSYLVAIN RAULTMAX ROBBA
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Keywords: ^1H-NMR
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1983 Volume 31 Issue 1 Pages 45-51

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Abstract
The synthesis of the new heterocycles pyrrolo [1', 2' : 1, 2] pyrazino [6, 5-b] carbazoles was achieved by the intramolecular cyclisation of 2-(1-pyrrolyl) carbazole derivatives. These latter compounds were obtained by the Clauson-Kaas reaction starting from the corresponding 2-aminocarbazoles, obtained by reduction of 2-nitrocarbazoles. A study of this reduction has shown that the introduction of acetyl grouping in position 9 makes this reaction easier and gives better results than previous methods. 1H-NMR spectra are studied.
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© The Pharmaceutical Society of Japan
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