TRIETHYLSILYLATION OF HYDROXYL GROUPS WITH A KETENE TRIETHYLSILYL ACETAL 2-METHYL-1-TRIETHYLSILYLOXY-1-METHOXYPROPENE

Abstract

A convenient O-triethylsilylation with dimethylketene triethylsilyl methyl acetal (1), which is prepared in excellent yield by catalytic hydrosilylation of methyl metacrylate is reported. Primary alcohols react readily at room temperature. Hindered alcohols are rapidly silylated in the presence of a trace amount of trifluoromethanesulfonic acid. For phenols heating with or without solvent is required.