An Improved Synthesis of N-(Butylaminocarbonyl)-4-hydroxymethyl-benzenesulfonamide, One of the Metabolites of Tolbutamide, and Synthesis of Its Formyl Derivative
Author's Organization:Faculty of Pharmaceutical Sciences, Nagasaki University Faculty of Pharmaceutical Sciences, Nagasaki University Faculty of Pharmaceutical Sciences, Nagasaki University
An improved synthesis of N-(butylaminocarbonyl)-4-hydroxymethyl-benzenesulfonamide, one of the metabolites of tolbutamide, and its transformation to the formyl derivative are described.