A Facile Preparation of 4-Thiazolone Derivatives from Thioamides and Various Haloacyl Halides in a Biphase System

抄録

The reaction of thioamides (1) with various haloacyl halides (2, 7, 11, 14, 17, and 19) was carried out in sat. NaHCO₃-CH₂Cl₂ and 5% NaOH-CH₂Cl₂ to give several kinds of 4-thiazolones (3-5, 10, 12 and 15), thiazin-4-one (18) and spiro compounds (21).