A New Tirucallane-Type Triterpenoid Derivative, Lipomelianol from Fruits of Melia toosendan SIEB. et ZUCC.

Abstract

A new tirucallane-type triterpenoid derivative, which we have named lipomelianol, has been obtained, together with a known triterpenoid, melianone (4), from fruits of Melia loosendan SIEB. et ZUCC. Lipomelianol was established to be a mixture of the 3-O-stearate, palmitate, myristate, and laurate (ca. 3 : 35 : 32 : 30) of melianol (3), as shown by formula 1, based on chemical, physico-chemical, and spectral evidence. High-resolution ¹³C-nuclear magnetic resonance data for 1, 3, and 4 are also reported.