Chemical Studies on the Constituents of the Thymelaeaceous Plants. II. : Stereochemistry of Daphnodorin A and Daphnodorin B

Abstract

The absolute configurations of daphnodorin A (1) and daphnodorin B (2) isolated from Daphne odora THUNB. (Thymelaeaceae) were studied, and 1 was assigned as C-2 (S), while 2 was assigned as C-2 (R), C-3 (S) on the basis of chemical transformations and spectral analyses. An X-ray analysis of daphnodorin A pentamethyl ether (4) was performed and two conformers (A and B) due to restricted rotation of the trioxy-benzoyl group were observed.