Steric Control for the Enantioselective Hydrolysis of Amino Acid Esters in Coaggregates Composed of Phosphatidylcholine and Triton X-100

Abstract

Remakably high enantioselectivity (L/D=19) along with marked enhancement of the hydrolytic cleavage of the L-form enantiomer (L-S₁₃) catalyzed by a tripeptide (Z-L-Phe-L-His-L-Leu) was attained by the use of specific coaggregates of 20 mol% dilauroylphosphatidylcholine and 80 mol% Triton X-100.