Sterodial Saponins and Alkaloids from the Bulbs of Lilium brownii var. colchesteri

Abstract

The fresh bulbs of Lilium brownii var. colchesteri were found to contain five steroidal saponins : 26-O-β-D-glucopyranosylnuatigenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (6), 26-O-β-D-glucopyranosylnuatigenin 3-O-α-L-rhamnopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-β-D-glucopyranoside (7), brownioside (8), deacylbrownioside (9) and 27-O-(3-hydroxy-3-methylglutaroyl)isonarthogenin 3-O-α-L-rhamnopyranosyl-(1→2)-O-[β-D-glicopyranosyl-(1→4)]-β-D-glucopyranoside (10); and two steroidal alkaloids : β₁-solamargine (11) and solasodine 3-O-α-L-rhamnopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)-β-D-glucopyranoside (12); along with several phenolic constituents. Compounds 7, 10 and 12 are new naturally-occurring compounds.