A FIRST TOTAL SYNTHESIS OF (±)-AMBININE

Miyoji HANAOKA; Won Jea CHO; Yoko SUGIURA; Chisato MUKAI

doi:10.1248/cpb.39.242

Miyoji HANAOKA, Won Jea CHO, Yoko SUGIURA, Chisato MUKAI

Author information

Keywords: ambinine, cis-hexahydrobenzo[<c>__-]phenanthridine, first total synthesis, protoberberine, 2, 3, 7, 8, 9-pentaoxygenated benzo[<c>__-]phenanthridine, isoquinolone

JOURNAL FREE ACCESS

1991 Volume 39 Issue 1 Pages 242-243

DOI https://doi.org/10.1248/cpb.39.242

Details

Abstract

A first total synthesis of (±)-ambinine (1) was completed using the 13-methylprotoberberine (10), a plausible biogenetic precursor, which could be prepared via the isoquinolone derivative (8).

Corresponding author

Register with J-STAGE for free!