Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Aldose Reductase Inhibitors from Natural Products. IV. Constituents and Aldose Reductase Inhibitory Effect of Chrysanthemum morifolium, Bixa orellana and Ipomoea batatas
寺島 恵清水 岑夫堀江 俊治森田 直賢
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1991 年 39 巻 12 号 p. 3346-3347

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The hot water extracts of Chrysanthemum morifolium, Bixa orellana and Ipomoea batatas, were found to have potent inhibitory activity towards lens aldose reductase (AR). Ellagic acid (4) was isolated from C. morifolium and I. batatas, isoscutellarein (7) from B. orellana and 3, 5-dicaffeoylquinic acid (10) from I. batatas, respectively, as potent inhibitors.
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© The Pharmaceutical Society of Japan
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