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Chemical and Pharmaceutical Bulletin
Vol. 39 (1991) No. 4 P 1041-1042

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http://doi.org/10.1248/cpb.39.1041


Taspine has been isolated as a cytotoxic substance from Sangre de Grado, sap of Croton palanostigma (Euphorbiaceae), by bioassay guided fractionation. The cytotoxicity (IC50) of taspine was found to be 0.39 μg/ml against KB cells and 0.17 μg/ml against V-79 cells.

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