Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Application of Liquid Particle Extraction to the Purification of Glycyrrhizin
西沢 秀幸沖村 早希子渡辺 右佳子阿部 芳広
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1991 年 39 巻 4 号 p. 969-971

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Glycyrrhizin on the market (about 90% in purity) contains two major impurities which are difficult to remove by recrystallization. Purification of a commercial sample was carried out by a dual-flow countercurrent extraction method, liquid particle extraction, which was recently introduced. Starting from 72.6 mg of commercial glycyrrhizin, it was purified to a purity of 99.7% with a recovery of 53.9% (35.3 mg).

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© The Pharmaceutical Society of Japan
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