Russuphelins B, C, D, E and F, New Cytotoxic Substances from the Mushroom Russula subnigricans HONGO

Akira TAKAHASHI; Tsutomu AGATSUMA; Tomihisa OHTA; Tetsuji NUNOZAWA; Takeshi ENDO; Shigeo NOZOE

doi:10.1248/cpb.41.1726

高橋昭, 我妻勉, 太田富久, 布沢哲二, 遠藤武, 野副重男

著者情報

キーワード: Russula subnigricans, russuphelin, cytotoxic substance, mushroom, basidiomycete, 2, 6-dichloro-1, 4-hydroquinone

ジャーナルフリー

1993 年 41 巻 10 号 p. 1726-1729

DOI https://doi.org/10.1248/cpb.41.1726

詳細

抄録

Five new chlorinated phenyl ethers, russuphelins B (2), C (3), D (4), E (5) and F (6) have been isolated from the mushroom Russula subnigricans HONGO, and their structures were elucidated by spectroscopic and chemical means. Russuphelins B (2), C (3) and D (4) exhibited cytotoxic activity in vitro against P388 leukemia cells.

責任著者(Corresponding author)

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