Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isolation of Camelliaside C from "Tea Seed Cake" and Inhibitory Effects of Its Derivatives on Arachidonate 5-Lipoxygenase
関根 利一新井 寧夫池上 文雄藤井 祐一進藤 省一郎柳澤 利彦石田 優子/ 村越 勇Isamu MURAKOSHI
ジャーナル フリー

1993 年 41 巻 6 号 p. 1185-1187


A new flavonol glycoside, camelliaside C, was isolated from "tea seed cake" prepared from the defatted seeds of Camellia sinensis O. KUNTZE. The structure was determined as kaempferol 3-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranoside by spectroscopic methods (FAB-MS, UV, IR, 1H- and 13C-NMR) and the enzymatic transformation of camelliaside C to astragalin. Camelliaside C showed an inhibitory effect on the arachidonate 5-lipoxygenase of RBL-1 cells (IC50 : 1.4×10-4 M) as did camelliaside A and B isolated from the same product.

© The Pharmaceutical Society of Japan
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