Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isolation of Cholesteryl Ester Transfer Protein Inhibitors form Panax ginseng Roots
Byoung-Mog KWONJi-Youn NAMSeung-Ho LEETae-Sook JEONGYoung-Kook KIMSong-Hae BOK
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1996 Volume 44 Issue 2 Pages 444-445

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Abstract

We have isolated cholesteryl ester transfer protein (CETP) inhibitors from the extract of Korean Panax ginseng C. A. MEYER roots and identified them as polyacetylene analogs. These compounds inhibit human CETP with IC50 values of around 20-35 mg/ml.

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© The Pharmaceutical Society of Japan
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