Enzymatic Hydrolysis of meso(syn-syn)-1, 3, 5-Triacetoxy-2, 4-dimethylpentane and Acetylation of meso(syn-syn)-3-Benzyloxy-2, 4-dimethylpentane-1, 5-diol by Lipase

Abstract

Chiral inductions of meso triacetate (4) and meso diol (15) were carried out on the basis of enzymatic reaction using lipase to give chiral synthons having three consecutive chiral centers with high enantiomeric excess.