Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ELECANACIN, A NOVEL NEW NAPHTHOQUINONE FROM THE BULB OF ELEUTHERINE AMERICANA
Hidemitsu HARANaoki MARUYAMAShinsuke YAMASHITAYasuhisa HAYASHIKuo-Hsiung LEEKenneth F. BASTOWCHAIRULRyuji MARUMOTOYasuhiro IMAKURA
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1997 Volume 45 Issue 10 Pages 1714-1716

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Abstract

A novel new naphthoquinone called elecanacin (9) and a new naphthalene called isoeleutherol (10) were isolated from the bulb of Eleutherine americana MERR. et HEYNE (Iridaceae), together with two known naphthoquinones (2 and 3). The structures were determined by spectroscopic methods including the 2D-NMR techniques. Eleutherin (2) showed interesting inhibitory activity against human topoisomerase II, and isoeleutherin (3) and isoeleutherol (10) showed inhibitory activity against HIV.

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