Preparation of Novel (1→3)-β-D-Glucans Having Reducing Glucose Side Chains

Abstract

Novel (1→3)-β-D-glucans (GPBCD, GPECD, GP6CD, and GP3CD) having reducing glucose side chains were prepared from a linear (1→3)-β-D-glucans (curdlan : CD) with halogeno glucose isopropylidene derivatives in dimethyl sulfoxide containing dimsyl sodium, followed by treatment with 40% trifluoroacetic acid to remove protecting isopropylidene groups. The side chain glucose moiety was linked directly or through a spacer at various positions except for its anomeric carbon.