Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
Bioactive Saponins and Glycosides. X. On the Constituents of Zizyphi Spinosi Semen, the Seeds of Zizyphus jujuba MILL. var. spinosa HU (1) : Structures and Histamine Release-Inhibitory Effects of Jujubosides A1 and C and Acetyljujuboside B
Masayuki YOSHIKAWAToshiyuki MURAKAMIAkira IKEBATAShuji WAKAONobutoshi MURAKAMIHisashi MATSUDAJohji YAMAHARA
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1997 Volume 45 Issue 7 Pages 1186-1192

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Abstract

New dammarane-type triterpene oligoglycosides, jujubosides A1 and C and acetyljujuboside B, were isolated from Zizyphi Spinosi Semen, the seeds of Zizyphus jujuba MILL. var. spinosa HU, together with three known saponins. The structures of jujubosides A1 and C and acetyljujuboside B were determined on the basis of chemical and physicochemical evidence.Jujubosides A1 and C and acetyljujuboside B were found to inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.

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© The Pharmaceutical Society of Japan
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