Synthesis of 2-Substituted 3-Nitro-1, 2-dihydropyridines by Heterocyclic Annulation Reactions of a sec-Nitrodienamine with Aldehyde Compounds

Takeshi KOIKE; Yoshifumi SHINOHARA; Noriko ISHIBASHI; Naoki TAKEUCHI; Seisho TOBINAGA

doi:10.1248/cpb.48.436

Takeshi KOIKE, Yoshifumi SHINOHARA, Noriko ISHIBASHI, Naoki TAKEUCHI, Seisho TOBINAGA

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Keywords: nitrodienamine, aldehyde, 2-substituted 3-nitro-1, 2-dihydropyridine, heterocyclic annulation reaction

JOURNAL FREE ACCESS

2000 Volume 48 Issue 3 Pages 436-439

DOI https://doi.org/10.1248/cpb.48.436

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Abstract

The reaction of a sec-nitrodienamine 3 with aldehyde compounds afforded 2-substituted 3-nitro-1, 2-dihydropyridines 5, providing a heterocyclic annulation reaction.

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