Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
On the Nitration of Quinoxalines.
乙益 寛隆仲嶋 正一
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1958 年 6 巻 5 号 p. 566-570

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Quinoxaline, quinoxaline N-oxide, and 2, 3-dimethylquinoxaline were resistant to nitration, but the quinoxaline derivatives containing polar functions, either in benzene or pyrazine ring, were readily nitrated. Thus, 5-methoxy-, 6-methoxy-, and 2-hydroxy-3-methyl-quinoxalines yielded upon nitration 5-methoxy-6, 8-dinitro-, 5-nitro-6-methoxy-and 2-hydroxy-3-methyl-6-nitro-quinoxalines, respectively.

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© The Pharmaceutical Society of Japan
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