Studies on Thiophene Derivatives. IV. Syntheses of 2-Aminoethyl 3, 3-Diaryl-3-hydroxypropanoates and 3, 3-Diaryl-2-prpenoates.
1960 年 8 巻 2 号 p. 103-107
詳細
1960 年 8 巻 2 号 p. 103-107
As some thiophene derivatives have interesting pharmacological action, 2-aminoethyl 3, 3-diaryl-3-hydroxypropanoates and 2-aminoethyl 3, 3-diaryl-2-propenoates having thiophene ring were synthesized. Esterification of3, 3-diaryl-3-hydroxypropanoic acids, prepared by the Reformatsky reaction of diaryl ketones, and 3, 3-diaryl-2-propenoic acid prepared by dehydration of these hydroxypropanoic acid gave aminoethyl esters of the corresponding acids.
