On the Nitration of Quinoxalines (Addendum)

Abstract

2-Hydroxyquinoxaline was nitrated with potassium nitrate in conc. sulfuric acid and formed 2-hydroxy-6-nitroquinoxaline, m.p. 306°, in 77% yield. This was treated with dimethyl sulfate and 1-methyl-2-oxo-6-nitro-1, 2-dihydroquinoxaline, m.p. 213°, was obtained, which was also prepared by the condensation of 1-methylamino-2-amino-4-nitrobenzene with butyl glyoxylate.