Bromo Derivatives of Cholestenone.

Abstract

Fission of 3α, 4α-epoxycholest-5-en-7-one with hydrobromic acid gave a bromohyrin, whose acyloxyl derivatives were converted to 4-bromocholesta-3, 5-dien-7-one, particularly to 6-bromocholesta-3, 5-dien-7-one accompanied with bromine migration. Also, 3, 4-dibromocholest-5-en-7-one was converted to 6-bromocholesta-3, 5-dienone. The ultraviolet and infrared absorption spectra of these bromo derivatives were summarized.