2002 Volume 67 Issue 3 Pages 309-321
Chromosomal aberrations (CA) and micronuclei polychromatic erythrocyte (MNPEC) from bone marrow cells of mice, and electrophoresis of B-esterase, lactate dehydrogenase and malate dehydrogenase from blood serum of mice were taken as an indication of the effects of electric field of strength 6 kV/m and frequency 50 Hz on the cytogenetic and isozyme electrophoresis. The chromosomal aberrations (CA) and micronuclei polychromatic erythrocytes (MNPEC) from bone marrow cells of mice were investigated after 30, 45 and 60 d of exposure to the electric, 4 mice were used for each period. The significant frequency of the chromosomal aberrations and MNPEC increased with increasing the time of exposure to the electric field. After switching off the power supply of the electric field, for a period late 30 d from post-exposure for 60 d. A progressive decrease in the chromosomal aberrations and MNPEC was noticed, but the percent of aberrations was still higher than that of the control. In the mean time, the mitotic index (MI) was also decreased when compared with the control. Also, the isozyme electrophoresis such as B-esterase and lactate dehydrogenase (Ldh) were slightly affected whereas malate dehydrogenase (Mdh) was not affected by ELFEF.
