Online ISSN : 1348-7019
Print ISSN : 0011-4545
Cytologia Focus
Computational Synteny Analysis Promotes a Better Understanding of Chromosome Evolution
Sachihiro MatsunagaAkihiro Nakaya
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2017 Volume 82 Issue 2 Pages 101-104


Synteny is modernly used to describe the conservation of homologous genomic regions between chromosomes among different species, although the term was first introduced to mean the gene location on the same chromosomes. Using database of whole genome sequences and web-tools for computational comparative analyses, we can find synteny blocks at high resolution and analyze chromosomal rearrangement among different species. Our constructed synteny maps between Oryza sativa and Arabidopsis thaliana or Zea mays reflected the evolutionary lineages of the plants. These computational synteny analyses contribute to the understanding of chromosome evolution and the discovery of the quantitative trait locus between related species. Future synteny analysis will include information of epigenome and three-dimensional chromatin organization.

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© 2017 The Japan Mendel Society
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