CYTOLOGIA
Online ISSN : 1348-7019
Print ISSN : 0011-4545
Regular Article
Cytotoxic Effects of Scutellaria discolor Colebr. Aqueous Extract in Allium cepa Root Tip Cells
Tista ChakrabortySanjib Ray
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2022 Volume 87 Issue 2 Pages 87-91

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Abstract

Scutellaria discolor Colebr. is a traditionally used annual herb that occurs in the Himalayan regions of India. The present study aimed to analyze the cytotoxic effects of S. discolor aqueous extract on Allium cepa root tip cells. The equal-sized roots, 48 h aged, were treated with the aqueous extract of S. discolor (AESD) (0.5–4 mg mL−1) and colchicine (0.4 mg mL−1) for 4 h continuously and then recovered for 16 h (4+16 h R) in distilled water. The AESD induced colchicine-like mitotic abnormalities; sticky chromosome, vagrant and laggard chromosomes, chromosomal fragments, anaphase bridges, stellate anaphase, micronucleus, and polyploidy, indicating it may have like colchicine prospective therapeutic and cytotoxic applications.

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© 2022 The Japan Mendel Society. Licensed under a Creative Commons Attribution 4.0 International (CC BY-NC-SA 4.0). https://creativecommons.org/licenses/by-nc-sa/4.0/

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 継承 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-sa/4.0/deed.ja
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